Firefox 4+ (*nix versions of Firefox have audio lockup bugs) - Retest this
Firefox 28+ (Web Audio API creates 500 ms or greater latency, forced by Firefox)
Opera (Crashes + Slow + Graphics Glitches) - Retest this
Safari 5.1.X (Below 5.1.5) (Slow or crashes)
IE 1-8 (Cannot run)
IE 9-10 (Slow, No native audio support (Requires flash bridge in the audio lib))
IE 11 (No native audio support (Requires flash bridge in the audio lib))
Firefox 1-3.6 (Slow)
ALL VERSIONS OF MOBILE SAFARI AND OPERA (Stop pestering me, iOS just CAN'T run this well.)
If you aren't using one of these, you should be fine.